- humanized antibody
- гуманизированное антителоантитела животного с помощью генной инженерии приведены в человеческую форму
English-Russian Biotechnology Glossary. A. F. Valikhov, V. V. Kolotvin, O. A. Legonkova, I. A. Rogov, Thomas Creamer. 2007.
humanized antibody
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Humanized antibody — Humanized antibodies or chimeric antibodies are a type of monoclonal antibody that have been synthesized using recombinant DNA technology to circumvent the clinical problem of immune response to foreign antigens. The standard procedure of… … Wikipedia
humanized antibody — Usually a mouse monoclonal antibody directed against a target of particular therapeutic value that has been modified to have all regions except the antigen binding portion substituted by human immunoglobulin domains. The procedure should make the … Dictionary of molecular biology
humanized monoclonal antibody — A type of antibody made in the laboratory by combining a human antibody with a small part of a mouse or rat monoclonal antibody. The mouse or rat part of the antibody binds to the target antigen, and the human part makes it less likely to be… … English dictionary of cancer terms
humanized — verb a monoclonal antibody derived from a mostly human source … Wiktionary
Monoclonal antibody therapy — Each antibody binds only one specific antigen. Monoclonal antibody therapy is the use of monoclonal antibodies (or mAb) to specifically bind to target cells or proteins. This may then stimulate the patient s immune system to attack those cells.… … Wikipedia
maytansinoid DM4-conjugated humanized monoclonal antibody huC242 — A substance being studied in the treatment of some types of cancer. It is made by linking the monoclonal antibody huC242 to a toxic substance called maytansinoid DM4. The monoclonal antibody locates and binds to the surfaces of cancer cells and… … English dictionary of cancer terms
Nomenclature of monoclonal antibodies — List of stems for monoclonal antibody nomenclature[1][2][3] … Wikipedia
Omalizumab — ? Monoclonal antibody Type Whole antibody Source Humanized (from mouse) Target IgE Fc region … Wikipedia
Cancer immunotherapy — is the use of the immune system to reject cancer. The main premise is stimulating the patient s immune system to attack the malignant tumor cells that are responsible for the disease. This can be either through immunization of the patient, in… … Wikipedia
IGKC — Immunoglobulin kappa constant, also known as IGKC, is a human gene that encodes a the constant domain of kappa type light chains for antibodies.cite web | title = Entrez Gene: IGKC immunoglobulin kappa constant| url =… … Wikipedia
IGHG1 — Immunoglobulin heavy constant gamma 1 (G1m marker), also known as IGHG1, is a human gene.cite web | title = Entrez Gene: IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene… … Wikipedia
